The 25-Cent Niagara stamp, issued in Washington, D.C., on November 11, 1922, pictures the American Falls on the Niagara River. The Niagara River, separating the United States from Canada, flows from Lake Erie into Lake Ontario. The source of the vignette is given in Bureau of Engraving and Printing records simply as "A photograph of Niagara Falls taken from Goat Island." Goat Island, also known as Luna Island, divides the American portion of Niagara Falls, shown on the stamp, from the Canadian portion of the falls, often called Horseshoe Falls.
Clair Aubrey Huston designed the stamp, Charles Chalmers engraved the vignette, and Edward E. Meyers engraved the variable lettering in the ribbon. Edward M Hall and Joachim C. Benzing engraved the frame.
Printed initially on the flat plate press, the stamp was later printed on the Stickney rotary press.